2 DISEASES INFLAMMATION What is inflammation is a complex biol,ogical response of vascular tissues to stimuli in a protective by the organism to remove the stimuli and to initiate the process. The typical signs of acute inflammation are pain, heat, redness, and loss of function. Inflammation is not a synonym of infection; in fact, it can occur without infection. It is a sort of stereotyped response and can be considered a mechanism of innate immunity. The factors that can stimulate inflammation include micro-organisms, physical agents, chemicals, inappropriate immunological responses, infectious agents such as viruses and bacteria, physical trauma, burns, radiation and . lt can also occur when tissue dies from lack of oxygen or nutrients, a situation often caused by loss of blood flow in the area. The first stage of inflammati,on is often called , which then becomes inflammation. Inflammation is followed by the discharging of pus. The granulation stage comes next, and new tissue is formed in the . Without inflammation, infections and wounds would never heal. Inflammation can be acute or chronic. Inflammation harmful 1 attempt injurious healing swelling frostbite irritation 1 wound WARM UP pain • heat • redness • swelling • bleeding • pus • pustules • loss of function of the organ involved What are the five cardinal signs of inflammation? Choose among the following: DO Do you know other adjectives ending in ? 1 -ful MORE lrritation also means being angry or upset. 1 Acute inflammation is the initi.al response of the body to harmful stimuli and is achieved by the increased movement of plasma and from the blood into the injured tissues. A series of biochemical events propagates and matures the inflammatory response involving the locai vascular system, the immune system and various cells within the injured tissue. Acute inflammation usually lasts six weeks or less and can result from many skin issues, like acne, sunburns and allergie reactions. Acute inflammation leukocytes Knee inflammation Chronic inflammation inflammation, or , leads to a progressive in the type of cells present at the site of inflammation and is characterised by simultaneous destruction and healing of the tissue from the inflammatory process. Chronic inflammation lasts more than six weeks and may be indefinite. Prolonged chronic inflammation shift